CBD and Parkinson’s Disease

CBD has shown potential in early studies for reducing dyskinetic activity in people with PD and treating motor symptoms in various neurodegenerative conditions.

According to a 2018 review study published by the journal Frontiers in Pharmacology, “Cannabidiol is a non-psychotomimetic compound from Cannabis sativa that presents antipsychotic, anxiolytic, anti-inflammatory, and neuroprotective effects.” Data also suggest that CBD could potentially play a protective role in the treatment of certain movement disorders. Results are promising, but further studies are needed to clarify the efficacy of CBD.

CBD has been shown to have anti-inflammatory, neuroprotective, and antioxidative effects in studies involving animal and human subjects. Both oxidative stress and inflammation play a role in Parkinson’s and all movement disorders to some extent. CBD has also been shown to have anti-anxiety properties, which helps patients who experience anxiety or depression and increased tremors caused by anxiety.

Most of the human studies that have evaluated CBD as a treatment for PD have focused on its potential to help with non-motor symptoms, such as psychotic symptoms, well-being, and sleep disorders. But a 2020 study published in the “Journal of Psychopharmacology” shows that CBD can reduce anxiety in PD patients, and consequently, the intensity of anxiety-related tremors. There is also research in animal models indicating that CBD may help with the management of motor symptoms.

Even though more studies need to be done to prove the efficacy of CBD in treating Parkinson’s, it does show hopeful results and can be used to help reduce symptoms stemming from the disease as well as side-effects caused by the medication.